The primary mechanism of action of ITI-1000 is to generate a T cell-mediated immune response against malignant glial cells expressing the CMV pp65 protein. View contacts for ImmunoMet Therapeutics to access new leads and connect with decision-makers. Pipeline - Immunomic Therapeutics The Company has built a pipeline leveraging UNITE with programs in oncology, animal health, infectious disease, and allergy. Immunomic Therapeutics investigational UNITE platform is founded in a combination of complementary technologies and capabilities: ITIs proprietary lysosomal targeting technology, optimal use of adjuvants, antigen selection and optimization, a breadth of delivery methods, and the ability to manufacture material at a large scale. ITI-1001 represents an off-the-shelf cancer immunotherapy approach that leverages ITIs proprietary UNITE platform to target CMV-associated antigens (pp65, IE-1 & gB) in Newly-Diagnosed Glioblastoma Multiforme (GBM).The primary mechanism of action of ITI-1001 is to enable specific presentation of the antigens via the lysosome mediated pathway in the antigen presenting cells (APC). If you enjoy the challenge that goes naturally with being part of a high growth company, then a career with Immunomic Therapeutics, Inc. may be just for you. Teri Heiland - Chief Scientific Officer (CSO) - Immunomic Therapeutics aanagnostou@immunomix.com IMU-935, a selective inverse agonist of the transcription factor RORt, is targeted for development in psoriasis, castration-resistant prostate cancer and Guillain-Barr syndrome. Pancreatic cancer is the fourth-most-common cause of cancer-related mortality in the USA. -Proceeds to support acceleration of Phase II clinical trial for GBM, advancement of pipeline, including development of COVID-19 vaccine candidate and expansion of opportunities for its UNITE nucleic acid platform-. This approach could put UNITE at the crossroads of immunotherapies in a number of illnesses, including cancer, allergy and infectious diseases. Hope versus experience in glioblastoma | Evaluate ITI-ID Candidate Multiple infectious diseases. It is one of the few malignancies for which incidence approximates prevalence, as patients almost always . The company's immunomodulation platform, LAMP-Vax, enables nucleic acid immunotherapy (DNA or RNA) to utilize the body's natural . A privately-held clinical stage biotechnology company pioneering the study of nucleic acid immunotherapy platforms | Immunomic Therapeutics, Inc. (ITI) is a privately-held clinical stage biotechnology company pioneering the study of the Universal Intracellular Targeted Expression (UNITE) nucleic acid immunotherapy platform. Request a free trial. 2017 Apr 15;23(8):1898-1909. 917-322-2571, Internet Explorer presents a security risk. To ensure the most secure and best overall experience on our website we recommend the latest versions of, Internet Explorer is no longer supported. ITI-1001 GBM - pDNA. The company held a successful pre-IND meeting earlier this year for ITI-1001 and expects to be able to file an Investigational New Drug Application (IND) with the U.S. Food and Drug Administration (FDA) by the end of 2020. Preclinical data is currently being developed to explore whether the UNITE platform may amplify and activate the immune response in highly immunogenic tumor types and be used to create immune responses to tumor types that otherwise do not provoke an immune response. Immunomic Therapeutics, Inc. Biotechnology Research Rockville, MD 2,335 followers A privately-held clinical stage biotechnology company pioneering the study of nucleic acid immunotherapy platforms HLB also secured an option to make further investment into the company in the months ahead. Contact Email info@immunomet.com. ImmunoMet Therapeutics is a development-stage biopharmaceutical company focused on the development and commercialization of novel oncology products . Senior Scientist/Scientist II, Formulation Development. The Company has built a large pipeline from UNITE with six oncology programs and two allergy programs. 1K followers 500+ connections. November 20, 2020-- Immunomic Therapeutics (ITI) and CoImmune Therapeutics have entered into a license agreement for ITI to use CoImmune's proprietary dendritic cell process for certain ITI cell therapy vaccine programs. We are looking for passionate individuals who want to create leading edge technology, thrive in an intellectually stimulating environment, and make a difference in healthcare outcomes. Our company has the capability to successfully plan, design and conduct clinical studies that enable us to establish POC in humans in a timely manner with the underlying capabilities to manufacture clinical trial supplies. If you enjoy the challenge that goes naturally with being part of a high growth company, then a career with Immunomic Therapeutics may be just for you. Chief Scientific Officer (CSO) Immunomic Therapeutics, Inc. Jun 2019 - Present3 years 9 months. Immunomic Therapeutics, Inc. | 2,335 followers on LinkedIn. Concurrent with the financing, five (5) members from HLB Co., LTD will be joining the Immunomic Therapeutics Board of Directors. Work Here? The first ITI oncology clinical program was born as a result of this decision and each subsequent asset in the pipeline represents a natural transition from this original point of entry into oncology. Su Y et al., CryJ-LAMP DNA Vaccines for Japanese Red Cedar Allergy Induce Robust Th1-Type Immune Responses in Murine Model. Jan 30, 2015. 2017 Aug;47:85-92. The company was founded in 2005 and is based in Lancaster, Pennsylvania. On behalf of the management team, I am pleased to welcome Ms. Harrison to ITI. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. The oncogenes E6 and E7 in both HPV 16 and HPV 18 strains are well proven to be immunogenic, providing the support to develop this product.ITI-2000, delivered by needle and syringe as a self-amplifying construct, will be indicated for HPV-positive cancers. Today, Brian Stamper, VP, Immunomic Therapeutics, will participate at #MTC's Annapolis Day 2023. Glioblastoma Multiforme (GBM) - Immunomic Therapeutics ITIs UNITE platform combines its core lysosomal targeting technology with novel formulation, delivery, and adjuvant complements. GBM patients white blood cells are removed, matured into dendritic cells and vaccinated against the pp65 viral protein, then returned to the patient. Nature. Home - Immunomic Therapeutics Brian joins the company with over 20 years of experience in cell therapy operations, pharmaceutical manufacturing, and process engineering. As a result, we make a significant investment in our employees through our Compensation, Health and Wellness, Retirement and Disability and Career Development programs. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. ITI is primarily focused on applying the UNITE platform to oncology, where it could potentially have broad applications, including antigen-derived antibodies as biologics. This employer has not claimed their Employer Profile and is missing out on connecting with our community. ITI is using the UNITE platform to develop vaccines against various infectious diseases, SARS-CoV-2 (COVID-19) among them. Immunomic Therapeutics, Inc. | LinkedIn Additionally, our expanded capabilities allow us to work with our corporate partners to better understand and develop the manufacturing process and product testing assays. The initial foray into immuno-oncology was undertaken when ITI decided to support the work of Drs. UNITE is a groundbreaking approach to vaccine development that has been applied to create vaccine candidates for rabies, yellow fever, dengue fever, hepatitis C and SARS, a relative to the SARS-CoV-2 coronavirus. Immunomic Therapeutics Announces Open Enrollment for RENEW Clinical Founded Date 2015. Find More Contacts for ImmunoMet Therapeutics, Edit Lists Featuring This Company Section, Dr. Revati Shreeniwas Joins ImmunoMet Therapeutics as Chief Medical Officer, ImmunoMet Therapeutics Appoints Vincent ONeill Chief Medical Officer, Health Care Companies With Less Than $1M in Revenue (Top 10K), Pharmaceutical Companies With Fewer Than 1000 Employees (Top 10K), Southern US Companies With Less Than $50M in Revenue (Top 10K). Claim your Free Employer Profile. April 23, 2020 04:00 PM Eastern Daylight Time. SaaS, Android, Cloud Computing, Medical Device). News | Astellas Pharma Inc. This approach could put UNITE technology at the crossroads of immunotherapies in a number of illnesses, including cancer, allergy and infectious diseases. View contacts for Immunomic Therapeutics to access new leads and connect with decision-makers. ICT has established a broad portfolio of CAR-T products to treat cancer patients. No.93, Zhongyang Rd., Xindian Dist., New Taipei City 231, Taiwan. Melody Carey Immunomic Therapeutics Announces the Appointment of Frances Harrison as Ms. Harrison brings to the company more than 30 years of experience in global regulatory strategies and submissions, interactions, intelligence and advocacy. ITI-2000 provides an UNITE platform address for HPV+ cancers. She succeeds Louise Peltier, Vice President of Regulatory Affairs, who retired on August 31, 2022. Immunic Therapeutics Investments & Acquisitions (2) Company Name Deal Date Deal Type Deal Size Industry Lead Partner; 00000 0000000: 12-Apr-2019: 0000000000: Drug Discovery: 000000 00: 4SC (immunology portfolio) 28-Sep-2016: You are here: hackberry allergy symptoms; 49ers paying players under the table; immunomic therapeutics crunchbase . 917-322-2571, Internet Explorer presents a security risk. Our Pipeline | Xilio Therapeutics 858-366-3243, Internet Explorer presents a security risk. Great people . ITIs lysosomal targeting technology is currently being employed in a Phase II clinical trial as a cancer immunotherapy. ITI-1000 GBM - Cell Therapy. We currently have 4 wholly-owned oncology programs, with our lead program in Phase 2 clinical studies for GBM. Immunomic Therapeutics, Inc. (ITI) is a privately-held, clinical stage biotechnology company pioneering the development of vaccines through its proprietary technology platform, UNiversal Intracellular Targeted Expression (UNITE), which is designed to utilize the bodys natural biochemistry to develop vaccines that generate broad immune responses. Cytokines secreted by CD4+ T cells, such as IFN, can also exert desirable effects on the tumor microenvironment. In addition to TH1 response, we also observe antigen specific antibodies indicative of TH2 response further enhancing the anti-tumor potential of this vaccine.ITI-1001 presents an alternative for patients that missed the treatment window for other therapies or that cannot produce enough cells to start cell therapy manufacturing (~30% of patients). Last Funding Type Venture - Series Unknown. We have significant capabilities in molecular biology, including nucleic acid vaccine design, immunology, and tumor mouse modeling. Since the Astellas deals, we have nearly doubled our research team to include deeper oncology expertise, including vaccinology, even neoantigen vaccine specialization. ITI-3000 is being tested in a Phase 1, open label, First in Human (FIH) study to evaluate the safety, tolerability, and immunogenicity of 4 mg of ITI-3000 in patients with Merkel polyomavirus-positive Merkel cell carcinoma (MCC). ITI granted Japanese animal health company, ZENOAQ (Nippon Zenyaku Kogyo Co., Ltd, Koriyama, Japan) an exclusive license to develop and commercialize its investigational DNA vaccine for canine atopic dermatitis and other companion animal allergies. Phone Number +4989208047700. While induction of tumor-reactive CD8+ T cells is a major goal of cancer therapy, CD4+ T cells provide essential support to CD8+ T cells by promoting their expression of cytotoxic effector molecules and increasing their migratory capacity. Curr Opin Immunol. Join to follow . Mr. Stamper holds a Master of Biotechnology Enterprise and Entrepreneurship Degree (MBEE) from Johns Hopkins University, a Master of Science Degree in Biologics Engineering from Purdue University, and a Bachelor of Science Degree in Biochemistry from Indiana University. immunomic therapeutics crunchbase. Frans broad experience and deep knowledge in regulatory affairs will be a tremendous asset during a critical time for ITI, as we continue our interactions with the FDA and other key regulatory agencies regarding our clinical programs, stated William Hearl, Ph.D., Immunomic Therapeutics Chief Executive Officer. The therapy was developed using ITIs proprietary UNITE (UNiversal Intracellular Targeted Expression) platform. Prior to joining ITI, Mr. Stamper held director roles in manufacturing at Kite Pharma, a global biopharmaceutical company whose focus is cell therapy to treat and cure cancer. View contacts for Immunic Therapeutics to access new leads and connect with decision-makers. Immunic is a clinical-stage biopharmaceutical company with a pipeline of selective oral immunology therapies focused on treating chronic inflammatory and autoimmune diseases. Immunomic Therapeutics, Inc. announced today that it has assumed sponsorship of the Investigational New Drug (IND) application for ITI-1000 from the University of Florida (UF). ITI-1000 is a dendritic cell therapy comprised of autologous dendritic cells (DCs) loaded with messenger ribonucleic acid (mRNA) encoding the human Lysosomal Associated Membrane Protein (hLAMP) gene fused in frame to a human Cytomegalovirus (hCMV) matrix protein, pp65 gene (hLAMP:pp65) and subsequently administered with Granulocyte-macrophage colony-stimulating factor (GM-CSF) and Tetanus/diphtheria (Td) toxoid which serve as adjuvants. ITI Company: Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. 2020 Immunomic Therapeutics, Inc. All Rights Reserved. Find More Contacts for Immunomic Therapeutics, Diversity Spotlight (US Headquarters Only). ITIs lysosomal targeting technology is currently being employed in a Phase II clinical trial as a cancer immunotherapy. Immunomic Therapeutics Strengthens Leadership Team with Appointment of Rockville, Maryland, 20850, United States. CONTACT US. Book the hotel with real traveler reviews, ratings and latest pictures of Chinatrust Executive House Hsin-Tien. Immunomic Therapeutics considers applicants for all positions without regard to race, color, creed, religion, ancestry, national origin, age, gender identity, sex, marital status, sexual orientation, physical or mental disability, use of a guide dog or service animal, military/veteran status, citizenship status, basis of genetic information, or any other group protected by law. Missing the target in cancer therapy | Nature Cancer But a few things must happen first. Immunomic Therapeutics is a development stage biotechnology company that develops lysosomal associated membrane protein-based vaccines for the treatment of allergy and other human health targets. Eric Winzer - CFO - Immunomic Therapeutics, Inc. | LinkedIn Copied SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Very family oriented. UNITE is currently being employed in Phase II clinical trials as a cancer immunotherapy. GBM patients white blood cells are removed, matured into dendritic cells and vaccinated against the pp65 viral protein, then returned to the patient. Global Brain Cancer Market Assessment 2021-2030 - PR Newswire Of special note are the following publications: To browse the literature, please see the curated list at PubMed. ImmunoMet Therapeutics is a development-stage biopharmaceutical company focused on the development and commercialization of novel oncology products that are aimed to improve the quality of life of cancer patients. Immunomic Therapeutics, Inc. (ITI) is a privately held, clinical stage biotechnology company pioneering the development of vaccines through its proprietary technology platform, UNiversal . For consideration, please send your company information, a copy of your standard search agreement, and references to: careers@immunomix.com. Immunomic Therapeutics' continued investment in Process Development provides value in several ways. Melssen M.,Vaccines targeting helper T cells for cancer immunotherapy. A successful transition from cell to cell-free therapy would provide broad validation to the ITI pDNA pipeline. ITI-2000 HPV+ Tumors. To ensure the most secure and best overall experience on our website we recommend the latest versions of, Internet Explorer is no longer supported. To explore Immunic Therapeutics's full profile, request access. You will receive a reply to confirm the receipt of your application. Sia Anagnostou Jan 2006 - Present17 years 2 months. We are delighted to welcome Brian to the Immunomic team, said William Hearl, Ph.D., Immunomic Therapeutics Chief Executive Officer. IMU-856, which targets the restoration of the intestinal barrier function, is targeted for development in diseases involving bowel barrier dysfunction. ITI-ID Candidate Multiple infectious diseases. What is health insurance like at Immunomic Therapeutics. As a result, a robust T cell response by both CD4+ and CD8+ T cells is expected to drive antitumor activity of this product. You can also compare prices and book all best hotels in New Taipei City with one-stop booking service on Trip.com. Our goal is to overcome the limitations of current immuno-oncology therapies by . The Immunomic Therapeutics, Inc. team includes specialists in the areas of science, process development, engineering, production, marketing, finance, human resources, quality and regulatory, administrative support and more. ITI-3000 Merkel Cell Carcinoma - pDNA. Su Y et al., Safety and long-term immunological effects of CryJ2-LAMP plasmid vaccine in Japanese red cedar atopic subjects: A phase I study. The company believes this approach may harness the bodys immune system to recognize, attack and destroy tumor cells that express CMV, which is over-expressed in GBM. Our portfolio includes more than 150 disruptive companies in areas ranging from the life sciences to engineering technology and digital health. Team - Immunomic Therapeutics ImmunoMet Therapeutics - Crunchbase Company Profile & Funding amy@juniper-point.com This feature is in beta and may change with future updates. 15010 Broschart Dr., Suite 110, Rockville, MD 20850. To ensure the most secure and best overall experience on our website, we recommend the latest versions of. We are a patient advocacy company that understands that patient enrollment in clinical trials is critical to advancements in medicine and patient treatment. We are looking for passionate individuals who want to create leading edge technology, thrive in an intellectually stimulating environment, and make a difference in healthcare outcomes. Find your private company bowl on Fishbowl, join the hottest conversation with your colleagues anonymously. Find More Contacts for Immunic Therapeutics, Edit Lists Featuring This Company Section, Immunic, Inc. In addition to TH1 response, we also observe antigen specific antibodies indicative of TH2 response further enhancing the anti-tumor potential of this vaccine.ITI-1001 presents an alternative for patients that missed the treatment window for other therapies or that cannot produce enough cells to start cell therapy manufacturing (~30% of patients). Find all information and best deals of Chinatrust Executive House Hsin-Tien, New Taipei City on Trip.com! It is important to note that, while the mechanism of lysosomal targeting appears to focus on enhancing presentation of antigen to CD4+ T cells and producing a Th1 type CD4+ T cell response (an aspect missing in other platforms), the UNITE platform, as a whole, is believed to induce a broad immune response and can result in enhanced CD8+ T cell responses as well. 2020 Immunomic Therapeutics, Inc. All Rights Reserved. ITI granted Japanese animal health company, ZENOAQ (Nippon Zenyaku Kogyo Co., Ltd, Koriyama, Japan) an exclusive license to develop and commercialize its investigational DNA vaccine for canine atopic dermatitis and other companion animal allergies. Immunomic Therapeutics is a biotech company committed to patients. New Taipei Municipal Hsin Tien Senior High School - Wikipedia View detailed 028300.KR description & address. ITIs investigational UNITE platform, or UNiversal Intracellular Targeted Expression, works by fusing pathogenic antigens with the Lysosomal Associated Membrane Protein, an endogenous protein in humans, for immune processing. ITI-2000 HPV+ Tumors. Report this profile . We now have a well-defined process to take things from ideation to in vivo animal proof of concept studies before handing them off to product development. Immunomic, Colmmune partner on cancer immunotherapy By The Science Advisory Board staff writers. Hum Vaccin Immunother. Operating Status Active. News Releases | PharmaJet Immunomic Therapeutics to present at the BIO CEO & Investor Conference Immunomic Therapeutics - Overview, News & Competitors | ZoomInfo.com Previously, Ms. Harrison served as Senior Vice President, Global Regulatory Affairs and Compliance at BTG International (now Boston Scientific). ITI Company: This is the Immunomic Therapeutics company profile. Arruda L.B., et al., Dendritic Cell-Lysosomal-Associated Membrane Protein (LAMP) and LAMP-1-HIV-1 Gag Chimeras Have Distinct Cellular Trafficking Pathways and Prime T and B Cell Responses to a Diverse Repertoire of Epitopes. Innovative Cellular Therapeutics (ICT) is a clinical-stage, VC-backed cell therapy company based in Rockville, MD. All content is posted anonymously by employees working at Immunomic Therapeutics.

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